Abdulrahim Abujayyab
Faculty of Medical and health Sciences – Liwa (Previous Emirates) College of Technology, Baniyas Tower 10th Floor – Abu Dhabi
Title: Anti-Diabetic Activity of Elaeagnus Commutate
Biography
Biography: Abdulrahim Abujayyab
Abstract
The hyperglycemic potential of Elaegnus Commutata was examined in this work in mice with normal, healthy blood sugar levels as well as animals with diabetes induced by alloxan. The administration of decoction and ethanolic extract of Elaeagnus Commutata to alloxan-treated mice produced a reduction of blood sugar levels. The ethanolic extract practically showed administration blood glucose level was lower as compared to the decoction-treated group. The tolbutamide effect was similar in trend: in our experiments, tolbutamide (200 mg/Kg) resulted in almost the same active (figure 3) in mice pretreated with high and low doses of alloxan (70 mg/kg & 45 mg/kg) as compared to the ethanolic extract (600 mg/Kg) treated group. Acute, subacute toxicity, and general pharmacology were also studied.
In conclusion: Elaegnus Commutata significantly reduced blood glucose levels in diabetic alloxanized mice while having little to no effect on blood glucose levels in the healthy control group of mice.