Day :
- Complementary & Alternative Medicine (CAM)
Session Introduction
Vaishali Shah
Associate professor, VIVA Institute of Pharmacy, India
Title: DEVELOPMENT AND EVALUATION OF POLYHERBAL FORMULATION FOR UROLITHIASIS
Biography:
Dr Vaishali Shah has completed her PHD at the age of 33 years from Gujarat University, India. She is working as an Associate professor at VIVA institute of Pharmacy Virar Mumbai, India since 2017. She has 26 publications and 7 Presentation in her research credit. She has guided 34 PG students She has also received minor research grant from Mumbai university and travel grant from AICTE. She is life member of APTI Association of Pharmacy teachers of India and ISP (Indian Society of Pharmacognosy
Abstract:
Urolithiasis, one of the most painful ailments of the urinary tract disorder, has beset humans from centuries. Medical treatments for kidney stone are relatively costly, painful and require expert hands and availability of appropriate equipments. So, the present research work had been undertaken for the Development and evaluation of polyherbal formulation for kidney stone. The formulation was developed using powders of Tribulus terrestris, Crataeva nurvala, Kalanchoe pinnata which are individually well reported in Ayurveda for Urolithiassis. Morphological, microscopical study and physicochemical parameters of all the plants present in formulations were done to identify the plants. The phytochemical screening was performed for presence of phytoconstituents. Total phenolic & total flavanoids content were calculated by Folin ciocalteau method and AlCl3 colorimetric method. Antioxidant activity was done by DPPH assay, Superoxide free radical scavenging activity & Reducing power assay. Anti-lithiatic acivity was performed by In vitro model- homogenous precipitation method. Phytochemical screening of formulation showed the presence of alkaloids, tannins, saponins, flavonoid. Total phenol and flavonoid content was 0.53 % and 0.51 % w/w respectively. It showed significant in vitro antioxidant activity in dose dependent manner as evident by antioxidant assay. Anti-lithiatic activity was performed which shows that the formulation has good anti-lithiatic activity and supports its tradional uses for kidney stone and showed synergistic effect in combination
Jessica Saleska
PhD MPH, Radicle Science, Encinitas, California
Title: The safety and comparative effectiveness of non-psychoactive cannabinoid formulations for the improvement of sleep: a double-blinded, randomized controlled trial
Biography:
Jessica Saleska, PhD, MPH, was awarded the T32 Fellowship to further her training in HIV treatment and prevention, focusing on the development of interventions informed by behavioral economics. Her background is in public health, having received her PhD in epidemiology from The Ohio State University and a Masters in Public Health from Washington University in St. Louis. Through her T32 Fellowship, she seeks to foster a deeper understanding of health decisions and behaviors through training and insights from psychology and economics. Her current research uses these insights to promote preventative health behaviors among adolescents, including the uptake of vaccines and the use of pre-exposure prophylaxis (PrEP) to prevent HIV acquisition. She has also spearheaded several multidisciplinary research collaborations between UCLA’s Semel Institute of Neuroscience and Human Behavior and UCLA’s Anderson School of Management to develop behavioral interventions for the prevention of COVID-19. When not involved in research and training, Jessica enjoys home-bartending and hiking with her partner and pup.
Abstract:
The objective of this randomized, double-blinded controlled trial was to evaluate the safety and comparative effectiveness of different formulations containing Cannabidiol (CBD) and melatonin, with and without the addition of minor cannabinoids, on sleep. Participants (N=1,793 adults experiencing symptoms of sleep disturbance) were assigned to receive a 4-week supply of 1 of 6 products (all capsules) containing either 15mg CBD or 5mg melatonin, alone or in combination with minor cannabinoids. Sleep disturbance was assessed using Patient-Reported Outcomes Measurement Information System (PROMIS™) Sleep Disturbance SF 8A, administered via weekly online surveys. All formulations exhibited a favorable safety profile (12% of participants reported a side effect and none were severe) and led to significant improvements in sleep disturbance (p<0.001 in within-group comparisons). Most participants (56% to 75%) across all formulations experienced a clinically important improvement in their sleep quality. There were no significant differences in effect, however, between 15mg CBD isolate and formulations containing 15mg CBD and 15mg Cannabinol (CBN), alone or in combination with 5 mg Cannabichromene (CBC). There were also no significant differences in effect between 15mg CBD isolate and formulations containing 5 mg melatonin, alone or in combination with 15mg CBD and 15mg CBN. Our findings suggest that chronic use of a low dose of CBD is safe and could improve sleep quality, though these effects do not exceed that of 5 mg melatonin. Moreover, the addition of low doses of CBN and CBC may not improve the effect of formulations containing CBD or melatonin isolate.
Erick Okek
Ugandan Ministry of Health as National Coordinator
Title: Effects of anti-malarial prophylaxes on maternal transfer of Immunoglobulin-G (IgG) and association to Immunity against Plasmodium falciparum infections among Children in a Ugandan birth Cohort
Biography:
Erick Okek (33 years) is a Ugandan scientist, program manager, politician and sports philanthropist, currently working at the Uganda Virus Research Institute (UVRI) and Ugandan Ministry of Health as National Coordinator for COVID19 and Arbovirology testing . He is Well trained and highly skilled scientist with Masters of Science degree in immunology and clinical microbiology (MICM) , adequately equipped with program management skills, coordination and leadership. Master’s degree was attained from Makerere University- college of health sciences (first class); currently Okek is pursuing a PhD in the same discipline and the same University, but with bias towards molecular immunology of plasmodium and malaria infections. Okek Erick has over ten years of intensive work experience in both research and clinical settings and has won several awards and accolades.
Away from academia and research, Okek stood for the Kwania county member of parliament in the 2021 Ugandan general election and narrowly lost to the incumbent member of parliament. He is also president of a local football club called Lira City Council Football club, currently playing in the 3rd division tier of Federation of Uganda Football Association (FUFA). He also doubles as Executive Director for Collaboration for Lango Development Association (COLADA); a Community based Organization with plethora of activities. Because of his love for humanity, Erick Okek Constructed and set up St.Getrude Community Health Center in the most remote and under priviledged settings in Northern Uganda (Apyelamot Village, Kwania district). This facility has been in existence for less than a year, but has saved over 500 lives, especially from malaria. His vision is to turn this place into center of excellence for management and Research of infectious diseases in Northern Uganda. Conclusively, Okek is a proud father of three girls and one boy.
Abstract:
Background:
The in-utero transfer of malaria specific IgG to the fetus in Plasmodium falciparum infected pregnant women potentially plays a role in provision of immune protection against malaria in the first birth year. However, the effect of Intermittent Prophylactic Treatment in Pregnancy (IPTp) and placental malaria on the extent of in-utero antibody transfer in malaria endemic regions like Uganda remain unknown. The aim of this study was thus to establish the effect of IPTp on in-utero transfer of malaria specific IgG to the fetus and the associated immune protection against malaria in the first birth year of children born to mothers who had P. falciparum infection during pregnancy in Uganda.
Methods:
We screened a total of 637 cord blood samples from a double blinded randomized clinical trial on Sulfadoxine-Pyrimethamine (SP) and Dihydroartemisinin-Piperaquine (DP) IPTp in a Ugandan birth cohort; study conducted from Busia, Eastern Uganda. Luminex assay was used to measure the cord levels of IgG sub-types (IgG1, IgG2, IgG3 and IgG4) against 15 different P. falciparum specific antigens, with tetanus toxoid (t.t) as a control antigen. Man-Whitney U test (non-parametric) in STATA (ver15) was used in statistical analysis of the samples. In addition, Multivariate cox regression analysis was used to determine the effect of maternal transfer of IgG on the incidence of malaria in the first birth year of children under study.
Results:
Mothers on SP expressed higher levels of cord IgG4 against erythrocyte binding antigens (EBA140, EBA175 and EBA181) (p<0.05). Placental malaria did not affect cord levels of IgG sub-types against selected P. falciparum specific antigens (p>0.05). Children who expressed higher levels (75th percentile) of total IgG against the six key P. falciparum antigens (Pf SEA, Rh4.2, AMA1, GLURP, Etramp5Ag1 and EBA 175) had higher risk of malaria in the first birth year; AHRs: 1.092, 95% CI: 1.02-1.17 (Rh4.2); 1.32, 95% CI: 1.00-1.74 (PfSEA); 1.21, 95%CI: 0.97-1.52 (Etramp5Ag1); 1.25, 95%CI: 0.98-1.60 (AMA1); 1.83, 95%CI: 1.15-2.93 (GLURP) (GLURP), and 1.35, ; 95%CI: 1.03-1.78 (EBA175). Children born to mothers categorized as poorest had the highest risk of malaria infections in the first birth year (AHR: 1.79, 95% CI: 1.31-2.4). Children born to mothers who had malaria infections during gestation had higher risk of getting malaria in the first birth year (AHR 1.30; 95%CI: 0.97- 1.7).
Conclusion
Malaria prophylaxis in pregnant mothers using either DP or SP does not affect expression of antibodies against P. falciparum specific antigens in the cord blood. Poverty and malaria infections during pregnancy are key risk factors of malaria infections in the first birth year of growth of children. Antibodies against P. falciparum specific antigens does not protect against parasitemia and malaria infections in the first birth year of children born in malaria endemic areas.
- Herbal Medicine
Session Introduction
Deanna Mulvihill
RN PhD, TLI Foundation, USA
Title: Women, trauma and alcohol dependency: Connections and disconnections in alcohol treatment for women
Biography:
Deanna Mulvihill has her expertise in evaluation and passion in improving the health and wellbeing. Her open and contextual evaluation model based on responsive constructivists creates new pathways for improving healthcare. She has built this model after years of experience in research, evaluation, teaching and administration both in hospital and education institutions.
Abstract:
Statement of the Problem: Women who have experienced intimate partnerviolence (IPV) are at greater risk for physical and mental health problems including posttraumatic stress disorder (PTSD) and alcohol dependency. On their own IPV, PTSD and alcohol dependency result in significant personal, social and economic cost and the impact of all three may compound these costs. Researchers have reported that women with these experiences are more difficult to treat; many do not access treatment and those who do, frequently do not stay because of difficulty maintaining helping relationships. However, these women’s perspective has not been previously studied. The purpose of this study is to describe the experience of seeking help for alcohol dependency by women with PTSD and a history of IPV in the context in which it occurs. Methodology & Theoretical Orientation: An inter subjective ethnographic study using hermeneutic dialogue was utilized during participant observation, in- depth interviews and focus groups. An ecological framework was utilized to focus on the interaction between the counselors and the staff to understand this relationships and the context in which it occurs. Findings: The women in this study were very active help seekers. They encountered many gaps in continuity of care including discharge because of relapse. Although the treatment center was a warm, healing and spiritual place, the women left the center without treatment for their trauma needs and many without any referral to address these outstanding issues. Conclusion & Significance: Women with alcohol dependence and PTSD with a history of IPV want help however the health and social services do not always recognize their calls for help or their symptoms of distress. Recommendations are made for treatment centers to become trauma- informed that would help this recognition.
Laila Shirbeigi
Department of Traditional Medicine, Tehran University of Medical Sciences
Title: Immunomodulatory Effects of Medicinal Plants used for Vitiligo in Traditional Persian Medicine
Biography:
Dr. Laila Shirbeigi MD, Ph.D. Associate Professor of Department of Traditional Medicine, School of Persian Medicine, with Scopus ID 57016683300 And Orcid No. 0000-0002-6503-8582. She has completed her PhD from Tehran University of Medical Sciences (TUMS). She is Dean of education of School of Persian Medicine.She has published 35 Papers in Scopus Indexed Journals and has been as an reviewer member of the journal named Tradirional Medicine Research.
Abstract:
Vitiligo is a hypopigmentation disorder that affects 1% of the world's population. Vitiligo causes white spots on the skin, mucous membranes, or white hair by destroying skin melanocytes. The pathogenesis of vitiligo is unknown but autoimmune, autocytotoxic, and neural mechanisms are suggested. According to the autoimmune theory, in people with vitiligo, immune cells invade and damage melanocytes. T cells are more commonly present in vitiligo patients' skin and remain in the lesion site, which is composed of CD8 and CD4 T cells. Many studies have been conducted on the presence and role of cytokines such as interleukins and interferongamma (IFN-γ) in the vitiligo process. Aim: This study aimed to introduce herbs effective against vitiligo from the perspective of Persian medicine and to investigate their possible therapeutic mechanisms with the possible effects of herbs on autoimmune mechanisms. Methods: For this purpose, keywords were used to extract data from Persian medicine textbooks, and then relevant scientific databases, including Google Scholar, PubMed, Web of Science, and Scopus were examined. Results: It was found that Persian medicine scholars used 50 different medicinal plants to treat and reduce the complications of vitiligo, and recent scientific studies have proven immune-regulating properties and reducing the effect of many of them on cytokines. Conclusion: According to scientific evidence on immunomodulatory effects, new research into the effects of these plants on vitiligo can lead to the discovery of new drugs and approaches for treating this diseas.
- Homeopathic Medicine
Session Introduction
Chris Chlebowski
NESH Alumni Practitioner Directory
Title: Treatment of SARS-CoV2 MRNA injection injuries using isopathic preparations of Aspergillus Niger
Biography:
Dr. Chris Chlebowski is naturopath, chiropractor, clinical herbalist, and homeopath. At his clinic, Ashland Natural Medicine in southern Oregon, Dr. Chlebowski and his staff use cutting-edge technology blended with traditional therapies. He specializes in helping patients recover from chronic Lyme disease, mold illness, cancer, neurological disorders, and—most commonly—“mystery” diseases that other doctors have been unable to diagnose.
Dr. Chlebowski lectures regularly on the root causes of illness and his articles have appeared in Naturopathic Doctor News and Review, Townsend Letter, and Simillimum. He holds medical degrees from Western States Chiropractic College and the National College of Natural Medicine.
Abstract:
Introduction: The rollout of the experimental MRNA injections for the treatment of SARS-CoV2 have resulted in a high number of injured patients. Injury types include, but are not limited to, neurological, mast cell activation, reactivation of quiescent infections, gastrointestinal distress, and autoimmune activation and reactivation. As conventional medicine has very little to offer these patients remedies from the natural world must be found to treat and cure these patients. Our clinical observations suggest that the use of commercially available preparations of diluted and potentized Aspergillus Niger resulted in improvement in a large percentage of patients.
Methods: All patients with SARS-CoV2 MRNA experimental injection injuries seen at the Phosphorus Center during a one-year period were enrolled in cohort study. Each patient underwent a comprehensive intake and examination, and when indicated, patients were given a preparation of diluted Aspergills Niger to self-administer at home between regular follow-up visits.
Results: All patients experienced improvement in their primary symptoms as well as marked improvement in ADL’s.
Conclusion: There is a significant decrease in symptoms and improvement in ADL’s in SARS-CoV2 injection injured patients treated with the use of a dilution of Aspergillus Niger. Further studies should be conducted to determine why this compound has utility in the context of injuries from the experimental SARS-CoV2 MRNA injections.
- Alternative Medicine & Treatment Method
Session Introduction
Joel Nudewhenu Logbo
CEO and founder of Mahc Alternatives Health Care Services, Nigeria
Title: Roles Of Natural Medicine Therapies In Management Of Cancers
Biography:
Joel Nudewhenu Logbo is a Lagos State Government Licensed herbalist, Chiropractor and lecturer at Lagos state college of health in department of Complementary And Alternative Health Sciences and a clinical researcher.He is member, Nigeria Council Of Physicians Of Natural Medicine, member, Association of Practitioners of Complementary And Alternative Medicine, Fellow, Chartered Institute Of Cooperatives And Social Enterprise Management and CEO, Mahc Alternative Medical Health Care Services. A health article writer with The Nation National Newspaper and Health Presenter, Kaftan TV. He has a Master's Degree in Public health and Doctorate Degree in Osteopathic Philosophy ( honorary causa) from Western Ville University, San Diego, USA respectively
Abstract:
Cancer is now a pandemic, killing thousands of people, male and female, children and old every year. Is one of the most researched health problem in recent years and costing millions of dollars for it management. Till today, many hardworking physicians are still working hard to get a permanent solution to cancers. Some form of cancer are highly fatal while some are not depending on the tissue it affects.
Chemotherapy and Radiotherapy has not provide any hope so far. The most promising therapies with success stories are from natural medicine sources which herbs are basic foundation for. We have many wonderful therapies that can help immune system, antineoplatic and powerful antioxidants among others powerful anticancer properties which need to be well researched on with clinical trials.
Follow me through my presentation as I unveil a powerful therapy for cancer management with several other chronic diseases. My hope is to see how some research organizations can invest into clinical trials of this therapy and others which evidence has shown are very effective in managing cancer of all types as we improve patients with cancers hope and also boost international collaborations and economy in this economic downturn era.
Zainab Noor
Homeopathic Docter Lahore, Pakistan
Title: P-FAMT-Piels And Fissures Alternative Medicine Treatment
Biography:
Homeopathic Docter Lahore, Pakistan
Abstract:
Piles are an enlargement of anal cushions at the distal rectum, while fissure is a tear in the skin in the lower anal canal.Piles are characterized with painless bleeding, while fissure presents severe pain and modest bleeding. Piles and fissure have different causes: Piles mostly occur after increased intraabdominal pressure resulting from obesity, age, or pregnancy, while fissure is mainly caused by anal trauma, and increased pressure in the anal canal.
- Blood in stool, Painful Bowel movements, Painful lump can be felt near the anus, Mucus discharge due to puss, Itching, and pain around the anal area.
- Tear around the anal area, Small lump near the tear, Painful bowel movements, blood in stool or toilet paper, Itching or burning sensation around the anal area
- Complementary & Alternative Medicine (CAM)
Session Introduction
Richard B. Aguilar
Clinical Assistant Professor, Nova Southeastern University
Title: The Addition Of A Single Dose of Platelet Rich Plasma (PRP) After Sarapin Therapy For Treatment Of Chronic Knee Pain In Elderly Patients In A Primary Care Setting
Biography:
Dr. Aguilar earned his MD degree in 1986 at the UC, Irvine College of Medicine where he completed his Internal Medicine residency. Dr. Aguilar is Clinical Assistant Professor, Nova Southeastern University, FL and Courtesy Clinical Associate Professor, Florida International University, FL. He has served as Chief of Medicine and Chief of ICU at several hospitals. In 2015, he became the CCO of Cano Health, LLC in South Florida. Growing the practice from one clinic to >150 clinics across 8 states. He has been invited to present internationally having given over 150 CME presentations in addition to publishing over 30 papers.
Abstract:
The efficacy of PRP in Chronic Knee Pain (CKP) has not been confirmed and usually requires up to 3 injections (1,2). Recently, significant improvement in CKP was reported in a cohort of 95 elderly patients following the administration of 3 weekly intraarticular injections of low cost aqueous Sarapin (3). This study sought to explore the effect of adding a single intraarticular injection of PRP to this cohort after completing the initial series of 3 Sarapin injections. A pain and functional limitation survey (a modified Lower Extremity Functional Scale (mLEFS)) was administered prior to initiating treatment (Entry Survey (ES)), one week After 3 Sarapin injections (AS) and then 30 (PRP30), 60 (PRP60), and 90 (PRP90) days after the single PRP injection. Higher scores denote a worse condition.
Results: N=95; Mean Age 62 +/- 9.8; 73% F; 89% Hispanic/Latino. Mean mLEFS pain/functional scores: ES 30.3 +/-12.1, AS 19.5 +/- 12.5, PRP30 18.46 +/- 13.9, PRP60 22.81 +/- 13.9, and PRP90 26.0 +/-13.9. The relative improvement in mLEFS scores compared to baseline (ES) were 39.0% PRP30 (P<0.0001), 24.7% PRP60 (P<0.001), and 14% PRP90 (P<0.036). No adverse events were reported.
Conclusions: In patients with CKP, a protocol using a single intraarticular injection of PRP after a course Sarapin resulted in significant improvement in pain and function for up to 120 days from baseline. PRP treatment can be costly ($400-1,500) (4). The use of a single dose of PRP after initial treatment with Sarapin, offers a sustained and cost-effective alternative treatment modality for CKP.
Mohammad Kamil
Director General, Lotus Holistic Health Institute, Abu Dhabi, UAE
Title: Quality Control and Standardization of Herbal Medicines & Herbal Medicinal Products
Biography:
Professor Mohammad Kamil: Ph.D.; D.Sc. Chartered Chemist (London); Fellow of Royal Society of Chemistry London, is Head TCAM Research, Zayed Complex for Herbal Research & Trad.Medicine, DHL&ME- DOH, Abu Dhabi, UAE .A recipient of Common Wealth Award-London; Convention Award of Chemical Society-India; Association of Common Wealth Universities -London; and Global award on Unani Medicine and various other prestigious honors & awards. Worked as in charge of Drug lab.MoH India, Professor at Jamia Hamdard University,. More than 350 papers and abstracts in reputed journals and international conferences are at his credit; chaired a no. of International Scientific sessions and presented invited talks as plenary and invited speaker at various International conferences / symposia. Associated with publication of many books; Author of a book besides five/six chapters in different books; Research work cited widely in books e.g. Advance in research, Chapman and Hall, London, New York;Melbourne; Studium Press,USA,UNIDO-Italy.
Abstract:
Abdulrahim Abujayyab
Faculty of Medical and health Sciences – Liwa (Previous Emirates) College of Technology, Baniyas Tower 10th Floor – Abu Dhabi
Title: Anti-Diabetic Activity of Elaeagnus Commutate
Biography:
Prof. Dr. Abu Jayyab is a Dean of Health Sciences & Medical Sciences and Medical at the Emirate University College of Technology (ECT), Abu Dhabi UAE. He also involves in the Design and Accreditation of Health and Medical Sciences at Emirates College of Technology (ECT); Prior to joining ECT, he was the Consultant of Academic Affairs, Chief Academic Officer &International Academic Advisor, at Royal Medical University. Amman, Jordan; Chairman of development of Medical and Health Programs at Syrian University for Science and Technology- Damascus. Syria. Member of Accreditation Committee and Head of the Internship and Training Central Committee (1999=2010) at Ajman University, UAE
Abstract:
The hyperglycemic potential of Elaegnus Commutata was examined in this work in mice with normal, healthy blood sugar levels as well as animals with diabetes induced by alloxan. The administration of decoction and ethanolic extract of Elaeagnus Commutata to alloxan-treated mice produced a reduction of blood sugar levels. The ethanolic extract practically showed administration blood glucose level was lower as compared to the decoction-treated group. The tolbutamide effect was similar in trend: in our experiments, tolbutamide (200 mg/Kg) resulted in almost the same active (figure 3) in mice pretreated with high and low doses of alloxan (70 mg/kg & 45 mg/kg) as compared to the ethanolic extract (600 mg/Kg) treated group. Acute, subacute toxicity, and general pharmacology were also studied.
In conclusion: Elaegnus Commutata significantly reduced blood glucose levels in diabetic alloxanized mice while having little to no effect on blood glucose levels in the healthy control group of mice.